How Porin Heterogeneity and Trade-Offs Affect the Antibiotic Susceptibility of Gram-Negative Bacteria

Variations in porin proteins are common in Gram-negative pathogens. Altered or absent porins reduce access of polar antibiotics across the outer membrane and can thus contribute to antibiotic resistance. Reduced permeability has a cost however, in lowering access to nutrients. This trade-off between...

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Detalles Bibliográficos
Autores principales: Ferenci, Thomas, Phan, Katherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Opinion
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690030/
https://www.ncbi.nlm.nih.gov/pubmed/26506392
http://dx.doi.org/10.3390/genes6041113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690030/
https://www.ncbi.nlm.nih.gov/pubmed/26506392
http://dx.doi.org/10.3390/genes6041113

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