COBRA-Seq: Sensitive and Quantitative Methylome Profiling

Combined Bisulfite Restriction Analysis (COBRA) quantifies DNA methylation at a specific locus. It does so via digestion of PCR amplicons produced from bisulfite-treated DNA, using a restriction enzyme that contains a cytosine within its recognition sequence, such as TaqI. Here, we introduce COBRA-s...

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Detalles Bibliográficos
Autores principales: Varinli, Hilal, Statham, Aaron L., Clark, Susan J., Molloy, Peter L., Ross, Jason P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690032/
https://www.ncbi.nlm.nih.gov/pubmed/26512698
http://dx.doi.org/10.3390/genes6041140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690032/
https://www.ncbi.nlm.nih.gov/pubmed/26512698
http://dx.doi.org/10.3390/genes6041140

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