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Super Enhancers in Cancers, Complex Disease, and Developmental Disorders

Recently, unique areas of transcriptional regulation termed super-enhancers have been identified and implicated in human disease. Defined by their magnitude of size, transcription factor density, and binding of transcriptional machinery, super-enhancers have been associated with genes driving cell d...

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Detalles Bibliográficos
Autores principales: Niederriter, Adrienne R., Varshney, Arushi, Parker, Stephen C. J., Martin, Donna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690034/
https://www.ncbi.nlm.nih.gov/pubmed/26569311
http://dx.doi.org/10.3390/genes6041183