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Membrane-Binding Mechanism of Clostridium perfringens Alpha-Toxin

Clostridium perfringens alpha-toxin is a key mediator of gas gangrene, which is a life-threatening infection that manifests as fever, pain, edema, myonecrosis, and gas production. Alpha-toxin possesses phospholipase C and sphingomyelinase activities. The toxin is composed of an N-terminal domain (1–...

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Detalles Bibliográficos
Autores principales: Oda, Masataka, Terao, Yutaka, Sakurai, Jun, Nagahama, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690130/
https://www.ncbi.nlm.nih.gov/pubmed/26633512
http://dx.doi.org/10.3390/toxins7124880