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Superantigen-Producing Staphylococcus aureus Elicits Systemic Immune Activation in a Murine Wound Colonization Model

Staphylococcus aureus, the most common cause of wound infection, produces several exotoxins, including superantigens (SAgs). SAgs are the potent activators of the immune system. Given this unique property, we hypothesized that SAgs produced by S. aureus in wounds would have local, as well as systemi...

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Detalles Bibliográficos
Autores principales: Kim, Choon K., Karau, Melissa J., Greenwood-Quaintance, Kerryl E., Tilahun, Ashenafi Y., Krogman, Ashton, David, Chella S., Pritt, Bobbi S., Patel, Robin, Rajagopalan, Govindarajan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690136/
https://www.ncbi.nlm.nih.gov/pubmed/26670252
http://dx.doi.org/10.3390/toxins7124886