Cargando…

Ion Channel Formation by Tau Protein: Implications for Alzheimer’s Disease and Tauopathies

[Image: see text] Tau is a microtubule associated protein implicated in the pathogenesis of several neurodegenerative diseases. Because of the channel forming properties of other amyloid peptides, we employed planar lipid bilayers and atomic force microscopy to test tau for its ability to form ion p...

Descripción completa

Detalles Bibliográficos
Autores principales: Patel, Nirav, Ramachandran, Srinivasan, Azimov, Rustam, Kagan, Bruce L., Lal, Ratnesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690196/
https://www.ncbi.nlm.nih.gov/pubmed/26575330
http://dx.doi.org/10.1021/acs.biochem.5b00988