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Ion Channel Formation by Tau Protein: Implications for Alzheimer’s Disease and Tauopathies
[Image: see text] Tau is a microtubule associated protein implicated in the pathogenesis of several neurodegenerative diseases. Because of the channel forming properties of other amyloid peptides, we employed planar lipid bilayers and atomic force microscopy to test tau for its ability to form ion p...
Autores principales: | Patel, Nirav, Ramachandran, Srinivasan, Azimov, Rustam, Kagan, Bruce L., Lal, Ratnesh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2015
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690196/ https://www.ncbi.nlm.nih.gov/pubmed/26575330 http://dx.doi.org/10.1021/acs.biochem.5b00988 |
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