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MixChIP: a probabilistic method for cell type specific protein-DNA binding analysis

BACKGROUND: Transcription factors (TFs) are proteins that bind to DNA and regulate gene expression. To understand details of gene regulation, characterizing TF binding sites in different cell types, diseases and among individuals is essential. However, sometimes TF binding can only be measured from...

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Detalles Bibliográficos
Autores principales: Rautio, Sini, Lähdesmäki, Harri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690251/
https://www.ncbi.nlm.nih.gov/pubmed/26703974
http://dx.doi.org/10.1186/s12859-015-0834-3