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MixChIP: a probabilistic method for cell type specific protein-DNA binding analysis
BACKGROUND: Transcription factors (TFs) are proteins that bind to DNA and regulate gene expression. To understand details of gene regulation, characterizing TF binding sites in different cell types, diseases and among individuals is essential. However, sometimes TF binding can only be measured from...
Autores principales: | Rautio, Sini, Lähdesmäki, Harri |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690251/ https://www.ncbi.nlm.nih.gov/pubmed/26703974 http://dx.doi.org/10.1186/s12859-015-0834-3 |
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