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Chronic binge alcohol administration dysregulates global regulatory gene networks associated with skeletal muscle wasting in simian immunodeficiency virus-infected macaques

BACKGROUND: There are more than 1 million persons living with HIV/AIDS (PLWHA) in the United States and approximately 40 % of them have a history of alcohol use disorders (AUD). Chronic heavy alcohol consumption and HIV/AIDS both result in reduced lean body mass and muscle dysfunction, increasing th...

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Detalles Bibliográficos
Autores principales: Simon, Liz, Hollenbach, Andrew D., Zabaleta, Jovanny, Molina, Patricia E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690320/
https://www.ncbi.nlm.nih.gov/pubmed/26699868
http://dx.doi.org/10.1186/s12864-015-2329-z