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Feasibility of focal cerebral ischemia and reperfusion surgery combined with chronic unpredictable mild stress to simulate the post-stroke depressive state in rats

OBJECTIVE: To evaluate the feasibility of focal cerebral ischemia and reperfusion (FCIR) surgery combined chronic unpredictable mild stress (CUMS) to simulate the post-stroke depression (PSD) state in rats. METHODS: Sprague–Dawley male rats were divided randomly into five groups: the normal, sham, F...

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Detalles Bibliográficos
Autores principales: Niu, Lingchuan, Jin, LiXinhao, Zhang, Yanhong, Liu, Bing, Li, Changqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690325/
https://www.ncbi.nlm.nih.gov/pubmed/26704068
http://dx.doi.org/10.1186/s12993-015-0085-5