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Feasibility of focal cerebral ischemia and reperfusion surgery combined with chronic unpredictable mild stress to simulate the post-stroke depressive state in rats
OBJECTIVE: To evaluate the feasibility of focal cerebral ischemia and reperfusion (FCIR) surgery combined chronic unpredictable mild stress (CUMS) to simulate the post-stroke depression (PSD) state in rats. METHODS: Sprague–Dawley male rats were divided randomly into five groups: the normal, sham, F...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690325/ https://www.ncbi.nlm.nih.gov/pubmed/26704068 http://dx.doi.org/10.1186/s12993-015-0085-5 |