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An efficient strategy for generation of transgenic mice by lentiviral transduction of male germline stem cells in vivo

BACKGROUND: Male germline stem cells (MGSCs) are a subpopulation of germ cells in the testis tissue. MGSCs are capable of differentiation into spermatozoa and thus are perfect targets for genomic manipulation to generate transgenic animals. METHOD: The present study was to optimize a protocol of pro...

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Detalles Bibliográficos
Autores principales:	Qin, Jinzhou, Xu, Haixia, Zhang, Pengfei, Zhang, Conghui, Zhu, Zhendong, Qu, Rongfeng, Qin, Yuwei, Zeng, Wenxian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690335/ https://www.ncbi.nlm.nih.gov/pubmed/26705472 http://dx.doi.org/10.1186/s40104-015-0058-4

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