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Complement C4 induces regulatory T cells differentiation through dendritic cell in systemic lupus erythematosus

BACKGROUND: Systemic lupus erythematosus (SLE) is a prototypic systemic autoimmune disease. Complement component 4 (C4) has be proved to play a role in pathogenesis of SLE. In the present study, we investigated the effect of C4 on T cells differentiation. METHODS: Thirty SLE patients were included i...

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Detalles Bibliográficos
Autores principales: Cheng, Hong-Bin, Chen, Rong-Yi, Wu, Jing-Ping, Chen, Li, Liang, Yan-Hua, Pan, Hai-Feng, Pan, Zi-Feng, Zhang, Qing-Hua, Li, Qing, Du, Tian-Xi, Lv, Yong-Mei, Shi, Jian-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690337/
https://www.ncbi.nlm.nih.gov/pubmed/26705467
http://dx.doi.org/10.1186/s13578-015-0052-8