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Orphan nuclear receptor NR4A2 inhibits hepatic stellate cell proliferation through MAPK pathway in liver fibrosis

Hepatic stellate cells (HSCs) play a crucial role in liver fibrosis, which is a pathological process characterized by extracellular matrix accumulation. NR4A2 is a nuclear receptor belonging to the NR4A subfamily and vital in regulating cell growth, metabolism, inflammation and other biological func...

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Detalles Bibliográficos
Autores principales: Chen, Pengguo, Li, Jie, Huo, Yan, Lu, Jin, Wan, Lili, Li, Bin, Gan, Run, Guo, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690364/
https://www.ncbi.nlm.nih.gov/pubmed/26713258
http://dx.doi.org/10.7717/peerj.1518