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Genome-wide identification of hypoxia-induced enhancer regions

Here we present a genome-wide method for de novo identification of enhancer regions. This approach enables massively parallel empirical investigation of DNA sequences that mediate transcriptional activation and provides a platform for discovery of regulatory modules capable of driving context-specif...

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Detalles Bibliográficos
Autores principales: Kamps-Hughes, Nick, Preston, Jessica L., Randel, Melissa A., Johnson, Eric A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690393/
https://www.ncbi.nlm.nih.gov/pubmed/26713262
http://dx.doi.org/10.7717/peerj.1527