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PI3 kinase mutations and mutational load as poor prognostic markers in diffuse glioma patients
INTRODUCTION: Recent advances in molecular diagnostics allow diffuse gliomas to be classified based on their genetic changes into distinct prognostic subtypes. However, a systematic analysis of all molecular markers has thus far not been performed; most classification schemes use a predefined and se...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690424/ https://www.ncbi.nlm.nih.gov/pubmed/26699864 http://dx.doi.org/10.1186/s40478-015-0265-4 |