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PI3 kinase mutations and mutational load as poor prognostic markers in diffuse glioma patients

INTRODUCTION: Recent advances in molecular diagnostics allow diffuse gliomas to be classified based on their genetic changes into distinct prognostic subtypes. However, a systematic analysis of all molecular markers has thus far not been performed; most classification schemes use a predefined and se...

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Detalles Bibliográficos
Autores principales: Draaisma, Kaspar, Wijnenga, Maarten M. J., Weenink, Bas, Gao, Ya, Smid, Marcel, Robe, P., van den Bent, Martin J., French, Pim J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690424/
https://www.ncbi.nlm.nih.gov/pubmed/26699864
http://dx.doi.org/10.1186/s40478-015-0265-4