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Cross-sector surveys assessing perceptions of key stakeholders towards barriers, concerns and facilitators to the appropriate use of adaptive designs in confirmatory trials

BACKGROUND: Appropriately conducted adaptive designs (ADs) offer many potential advantages over conventional trials. They make better use of accruing data, potentially saving time, trial participants, and limited resources compared to conventional, fixed sample size designs. However, one can argue t...

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Detalles Bibliográficos
Autores principales: Dimairo, Munyaradzi, Julious, Steven A., Todd, Susan, Nicholl, Jonathan P., Boote, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690427/
https://www.ncbi.nlm.nih.gov/pubmed/26700741
http://dx.doi.org/10.1186/s13063-015-1119-x