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Whole-genome bisulfite sequencing maps from multiple human tissues reveal novel CpG islands associated with tissue-specific regulation

CpG islands (CGIs) are one of the most widely studied regulatory features of the human genome, with critical roles in development and disease. Despite such significance and the original epigenetic definition, currently used CGI sets are typically predicted from DNA sequence characteristics. Although...

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Detalles Bibliográficos
Autores principales: Mendizabal, Isabel, Yi, Soojin V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690492/
https://www.ncbi.nlm.nih.gov/pubmed/26512062
http://dx.doi.org/10.1093/hmg/ddv449