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Rab9A is required for delivery of cargo from recycling endosomes to melanosomes

Melanosomes are a type of lysosome-related organelle that is commonly defective in Hermansky–Pudlak syndrome. Biogenesis of melanosomes is regulated by BLOC-1, -2, -3, or AP-1, -3 complexes, which mediate cargo transport from recycling endosomes to melanosomes. Although several Rab GTPases have been...

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Detalles Bibliográficos
Autores principales: Mahanty, Sarmistha, Ravichandran, Keerthana, Chitirala, Praneeth, Prabha, Jyothi, Jani, Riddhi Atul, Setty, Subba Rao gangi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690521/
https://www.ncbi.nlm.nih.gov/pubmed/26527546
http://dx.doi.org/10.1111/pcmr.12434