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Characterization of the role of HCN channels in β3-adrenoceptor mediated rat bladder relaxation

OBJECTIVE: The second messenger cAMP is involved in both β3 adrenoceptor (β3-AR) mediated detrusor relaxation and the kinetics of Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels. Here we characterized the effect HCN channel activation and possible interaction with β3-AR in bladder...

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Detalles Bibliográficos
Autores principales: Kashyap, Mahendra, Yoshimura, Naoki, Smith, Phillip P., Chancellor, Michael, Tyagi, Pradeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690542/
https://www.ncbi.nlm.nih.gov/pubmed/26709376
http://dx.doi.org/10.14440/bladder.2015.44