Cargando…

Characterization of the role of HCN channels in β3-adrenoceptor mediated rat bladder relaxation

OBJECTIVE: The second messenger cAMP is involved in both β3 adrenoceptor (β3-AR) mediated detrusor relaxation and the kinetics of Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels. Here we characterized the effect HCN channel activation and possible interaction with β3-AR in bladder...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kashyap, Mahendra, Yoshimura, Naoki, Smith, Phillip P., Chancellor, Michael, Tyagi, Pradeep
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690542/ https://www.ncbi.nlm.nih.gov/pubmed/26709376 http://dx.doi.org/10.14440/bladder.2015.44

Ejemplares similares

Intravesical Liposome and Antisense Treatment for Detrusor Overactivity and Interstitial Cystitis/Painful Bladder Syndrome
por: Tyagi, Pradeep, et al.
Publicado: (2014)

β-Adrenoceptor-mediated Relaxation of Urinary Bladder Muscle in β(2)-Adrenoceptor Knockout Mice
por: Propping, Stefan, et al.
Publicado: (2016)

Effect of pre-contraction on β-adrenoceptor-mediated relaxation of rat urinary bladder
por: Michel, Martin Christian, et al.
Publicado: (2009)

Functional role of cannabinoid receptors in urinary bladder
por: Tyagi, Pradeep, et al.
Publicado: (2010)

β(3)-Adrenoceptor-mediated relaxation of rat and human urinary bladder: roles of BK(Ca) channels and Rho kinase
por: Cernecka, Hana, et al.
Publicado: (2015)

Functional and Molecular Characterization of Hyposensitive Underactive Bladder Tissue and Urine in Streptozotocin-Induced Diabetic Rat
por: Nirmal, Jayabalan, et al.
Publicado: (2014)

Human Urinary Bladder Strip Relaxation by the β-Adrenoceptor Agonist Isoprenaline: Methodological Considerations and Effects of Gender and Age
por: Schneider, Tim, et al.
Publicado: (2011)

Serelaxin Elicits Bronchodilation and Enhances β-Adrenoceptor-Mediated Airway Relaxation
por: Lam, Maggie, et al.
Publicado: (2016)

β-Adrenoceptor subtypes and cAMP role in adrenaline- and noradrenaline-induced relaxation in the rat thoracic aorta
por: Shiina, Shunsuke, et al.
Publicado: (2018)

HCN Channels and Heart Rate
por: Scicchitano, Pietro, et al.
Publicado: (2012)

Review: HCN Channels in the Heart
por: Depuydt, Anne-Sophie, et al.
Publicado: (2022)

Effects of sitagliptin on ß-adrenoceptor mediated relaxation in streptozotocin-diabetic rat aorta
por: MÜDERRİSOĞLU, Ayhanım Elif, et al.
Publicado: (2021)

Can [(125)I]-Iodocyanopindolol Label β(3)-Adrenoceptors in Rat Urinary Bladder?
por: Schneider, Tim, et al.
Publicado: (2010)

Effect of Suo Quan Wan on the bladder function of aging rats based on the β-adrenoceptor
por: Xu, Yi-Fei, et al.
Publicado: (2017)

STABILIZING ROLE OF HCN CHANNELS ON POST-CAMP MECHANISMS OF DETRUSOR MYOCYTE CONTROL
por: Ramasamy, Ramalakshmi, et al.
Publicado: (2022)

Characterization of drug binding within the HCN1 channel pore
por: Tanguay, Jérémie, et al.
Publicado: (2019)

Inflammasomes are important mediators of prostatic inflammation associated with BPH
por: Kashyap, Mahendra, et al.
Publicado: (2015)

On the Site and Mechanism of Action of β(3)-Adrenoceptor Agonists in the Bladder
por: Andersson, Karl Erik
Publicado: (2017)

Activation gating in HCN2 channels
por: Hummert, Sabine, et al.
Publicado: (2018)

HCN Channels Modulators: The Need for Selectivity
por: Romanelli, Maria Novella, et al.
Publicado: (2016)

Regulation of HCN Channels by Protein Interactions
por: Peters, Colin H., et al.
Publicado: (2022)

A Clinician’s Perspective on the Mechanism of β(3)-Adrenoceptor Agonists in the Bladder
por: Lee, Tack
Publicado: (2017)

Gabapentin Modulates HCN4 Channel Voltage-Dependence
por: Tae, Han-Shen, et al.
Publicado: (2017)

S4 Movement in a Mammalian HCN Channel
por: Vemana, Sriharsha, et al.
Publicado: (2004)

HCN Channels—Modulators of Cardiac and Neuronal Excitability
por: Herrmann, Stefan, et al.
Publicado: (2015)

Dysfunctional HCN ion channels in neurological diseases
por: DiFrancesco, Jacopo C., et al.
Publicado: (2015)

Beta3-Adrenoceptor Agonists: Possible Role in the Treatment of Overactive Bladder
por: Igawa, Yasuhiko, et al.
Publicado: (2010)

HCN Channel Modulation of Synaptic Integration in GABAergic Interneurons in Malformed Rat Neocortex
por: Albertson, Asher J., et al.
Publicado: (2017)

Functional Characterization of Cnidarian HCN Channels Points to an Early Evolution of I(h)
por: Baker, Emma C., et al.
Publicado: (2015)

Functional and structural characterization of interactions between opposite subunits in HCN pacemaker channels
por: Kondapuram, Mahesh, et al.
Publicado: (2022)

Selective Blockade of HCN1/HCN2 Channels as a Potential Pharmacological Strategy Against Pain
por: Dini, Leonardo, et al.
Publicado: (2018)

Changes in peripheral HCN2 channels during persistent inflammation
por: Jansen, L-A. R., et al.
Publicado: (2021)

Bladder Uptake of Liposomes after Intravesical Administration Occurs by Endocytosis
por: Rajaganapathy, Bharathi Raja, et al.
Publicado: (2015)

Salts of HCN‐Cyanide Aggregates: [CN(HCN)(2)](−) and [CN(HCN)(3)](−)
por: Bläsing, Kevin, et al.
Publicado: (2020)

Integrated Allosteric Model of Voltage Gating of Hcn Channels
por: Altomare, Claudia, et al.
Publicado: (2001)

Cooperative Gating between Single HCN Pacemaker Channels
por: Dekker, John P., et al.
Publicado: (2006)

The Role of HCN Channels on Membrane Excitability in the Nervous System
por: Kase, Daisuke, et al.
Publicado: (2012)

Isoform dependent regulation of human HCN channels by cholesterol
por: Fürst, Oliver, et al.
Publicado: (2015)

HCN Channels: New Therapeutic Targets for Pain Treatment
por: Ramírez, David, et al.
Publicado: (2018)

A Possible Link Between HCN Channels and Depression
por: Kim, Chung Sub, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_kvm7vjtj7moropsh2d1fvoa8ch