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Effects of Incorporating Carboxymethyl Chitosan into PMMA Bone Cement Containing Methotrexate

Treatment of bone metastases usually includes surgical resection with local filling of methotrexate (MTX) in polymethyl methacrylate (PMMA) cement. We investigated whether incorporating carboxymethyl chitosan (CMCS) in MTX-PMMA cement might overcome disadvantages associated with MTX. To determine th...

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Detalles Bibliográficos
Autores principales: Liu, Bo-Ming, Li, Ming, Yin, Bao-Sheng, Zou, Ji-Yang, Zhang, Wei-Guo, Wang, Shou-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690603/
https://www.ncbi.nlm.nih.gov/pubmed/26657526
http://dx.doi.org/10.1371/journal.pone.0144407