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Effects of Incorporating Carboxymethyl Chitosan into PMMA Bone Cement Containing Methotrexate
Treatment of bone metastases usually includes surgical resection with local filling of methotrexate (MTX) in polymethyl methacrylate (PMMA) cement. We investigated whether incorporating carboxymethyl chitosan (CMCS) in MTX-PMMA cement might overcome disadvantages associated with MTX. To determine th...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690603/ https://www.ncbi.nlm.nih.gov/pubmed/26657526 http://dx.doi.org/10.1371/journal.pone.0144407 |