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A pilot study of serotonin-1A receptor genotypes and rapid eye movement sleep sensitivity to serotonergic/cholinergic imbalance in humans: a pharmacological model of depression

RATIONALE: The serotonergic and cholinergic systems are jointly involved in regulating sleep but this system is theorized to be disturbed in depressed individuals. We previously reported that cholinergic and serotonergic agents induce sleep changes partially consistent with monoamine models of sleep...

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Detalles Bibliográficos
Autores principales: Biard, Kathleen, Douglass, Alan B, Robillard, Rébecca, De Koninck, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690650/
https://www.ncbi.nlm.nih.gov/pubmed/26719734
http://dx.doi.org/10.2147/NSS.S94549