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Regulation of Cholesterol Homeostasis by Hedgehog Signaling in Osteoarthritic Cartilage
OBJECTIVE: With no effective therapies to attenuate cartilage degeneration in osteoarthritis (OA), the result is pain and disability. Activation of hedgehog (HH) signaling causes changes related to the progression of OA, with higher levels of Gli‐mediated transcriptional activation associated with i...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690757/ https://www.ncbi.nlm.nih.gov/pubmed/26315393 http://dx.doi.org/10.1002/art.39337 |