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Fluorescent Protein-Tagged Sindbis Virus E2 Glycoprotein Allows Single Particle Analysis of Virus Budding from Live Cells

Sindbis virus (SINV) is an enveloped, mosquito-borne alphavirus. Here we generated and characterized a fluorescent protein-tagged (FP-tagged) SINV and found that the presence of the FP-tag (mCherry) affected glycoprotein transport to the plasma membrane whereas the specific infectivity of the virus...

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Detalles Bibliográficos
Autores principales: Jose, Joyce, Tang, Jinghua, Taylor, Aaron B., Baker, Timothy S., Kuhn, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690852/
https://www.ncbi.nlm.nih.gov/pubmed/26633461
http://dx.doi.org/10.3390/v7122926