Potential for Improving Potency and Specificity of Reovirus Oncolysis with Next-Generation Reovirus Variants

Viruses that specifically replicate in tumor over normal cells offer promising cancer therapies. Oncolytic viruses (OV) not only kill the tumor cells directly; they also promote anti-tumor immunotherapeutic responses. Other major advantages of OVs are that they dose-escalate in tumors and can be gen...

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Detalles Bibliográficos
Autores principales: Mohamed, Adil, Johnston, Randal N., Shmulevitz, Maya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690860/
https://www.ncbi.nlm.nih.gov/pubmed/26633466
http://dx.doi.org/10.3390/v7122936

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690860/
https://www.ncbi.nlm.nih.gov/pubmed/26633466
http://dx.doi.org/10.3390/v7122936

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