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Potential for Improving Potency and Specificity of Reovirus Oncolysis with Next-Generation Reovirus Variants
Viruses that specifically replicate in tumor over normal cells offer promising cancer therapies. Oncolytic viruses (OV) not only kill the tumor cells directly; they also promote anti-tumor immunotherapeutic responses. Other major advantages of OVs are that they dose-escalate in tumors and can be gen...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690860/ https://www.ncbi.nlm.nih.gov/pubmed/26633466 http://dx.doi.org/10.3390/v7122936 |