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From Immunodeficiency to Humanization: The Contribution of Mouse Models to Explore HTLV-1 Leukemogenesis

The first discovered human retrovirus, Human T-Lymphotropic Virus type 1 (HTLV-1), is responsible for an aggressive form of T cell leukemia/lymphoma. Mouse models recapitulating the leukemogenesis process have been helpful for understanding the mechanisms underlying the pathogenesis of this retrovir...

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Detalles Bibliográficos
Autores principales: Pérès, Eléonore, Bagdassarian, Eugénie, This, Sébastien, Villaudy, Julien, Rigal, Dominique, Gazzolo, Louis, Duc Dodon, Madeleine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690867/
https://www.ncbi.nlm.nih.gov/pubmed/26690200
http://dx.doi.org/10.3390/v7122944