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Two Cytoplasmic Acylation Sites and an Adjacent Hydrophobic Residue, but No Other Conserved Amino Acids in the Cytoplasmic Tail of HA from Influenza A Virus Are Crucial for Virus Replication

Recruitment of the matrix protein M1 to the assembly site of the influenza virus is thought to be mediated by interactions with the cytoplasmic tail of hemagglutinin (HA). Based on a comprehensive sequence comparison of all sequences present in the database, we analyzed the effect of mutating conser...

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Detalles Bibliográficos
Autores principales: Siche, Stefanie, Brett, Katharina, Möller, Lars, Kordyukova, Larisa V., Mintaev, Ramil R., Alexeevski, Andrei V., Veit, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690873/
https://www.ncbi.nlm.nih.gov/pubmed/26670246
http://dx.doi.org/10.3390/v7122950