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Potential Broad Spectrum Inhibitors of the Coronavirus 3CL(pro): A Virtual Screening and Structure-Based Drug Design Study

Human coronaviruses represent a significant disease burden; however, there is currently no antiviral strategy to combat infection. The outbreak of severe acute respiratory syndrome (SARS) in 2003 and Middle East respiratory syndrome (MERS) less than 10 years later demonstrates the potential of coron...

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Detalles Bibliográficos
Autores principales: Berry, Michael, Fielding, Burtram C., Gamieldien, Junaid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690886/
https://www.ncbi.nlm.nih.gov/pubmed/26694449
http://dx.doi.org/10.3390/v7122963