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Ebola Virus Infections in Nonhuman Primates Are Temporally Influenced by Glycoprotein Poly-U Editing Site Populations in the Exposure Material

Recent experimentation with the variants of the Ebola virus that differ in the glycoprotein’s poly-uridine site, which dictates the form of glycoprotein produced through a transcriptional stutter, has resulted in questions regarding the pathogenicity and lethality of the stocks used to develop produ...

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Detalles Bibliográficos
Autores principales: Trefry, John C., Wollen, Suzanne E., Nasar, Farooq, Shamblin, Joshua D., Kern, Steven J., Bearss, Jeremy J., Jefferson, Michelle A., Chance, Taylor B., Kugelman, Jeffery R., Ladner, Jason T., Honko, Anna N., Kobs, Dean J., Wending, Morgan Q.S., Sabourin, Carol L., Pratt, William D., Palacios, Gustavo F., Pitt, M. Louise M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690892/
https://www.ncbi.nlm.nih.gov/pubmed/26703716
http://dx.doi.org/10.3390/v7122969