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Does Lysosomial Acid Lipase Reduction Play a Role in Adult Non-Alcoholic Fatty Liver Disease?

Lysosomal Acid Lipase (LAL) is a key enzyme involved in lipid metabolism, responsible for hydrolysing the cholesteryl esters and triglycerides. Wolman Disease represents the early onset phenotype of LAL deficiency rapidly leading to death. Cholesterol Ester Storage Disease is a late onset phenotype...

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Detalles Bibliográficos
Autores principales: Baratta, Francesco, Pastori, Daniele, Polimeni, Licia, Tozzi, Giulia, Violi, Francesco, Angelico, Francesco, Del Ben, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691032/
https://www.ncbi.nlm.nih.gov/pubmed/26602919
http://dx.doi.org/10.3390/ijms161226085