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Intravenous Administration of Cilostazol Nanoparticles Ameliorates Acute Ischemic Stroke in a Cerebral Ischemia/Reperfusion-Induced Injury Model

It was reported that cilostazol (CLZ) suppressed disruption of the microvasculature in ischemic areas. In this study, we have designed novel injection formulations containing CLZ nanoparticles using 0.5% methylcellulose, 0.2% docusate sodium salt, and mill methods (CLZ(nano) dispersion; particle siz...

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Detalles Bibliográficos
Autores principales: Nagai, Noriaki, Yoshioka, Chiaki, Ito, Yoshimasa, Funakami, Yoshinori, Nishikawa, Hiroyuki, Kawabata, Atsufumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691110/
https://www.ncbi.nlm.nih.gov/pubmed/26690139
http://dx.doi.org/10.3390/ijms161226166