Domain Motions and Functionally-Key Residues of l-Alanine Dehydrogenase Revealed by an Elastic Network Model

Mycobacterium tuberculosis l-alanine dehydrogenase (l-MtAlaDH) plays an important role in catalyzing l-alanine to ammonia and pyruvate, which has been considered to be a potential target for tuberculosis treatment. In the present work, the functional domain motions encoded in the structure of l-MtAl...

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Detalles Bibliográficos
Autores principales: Li, Xing-Yuan, Zhang, Jing-Chao, Zhu, Yan-Ying, Su, Ji-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691113/
https://www.ncbi.nlm.nih.gov/pubmed/26690143
http://dx.doi.org/10.3390/ijms161226170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691113/
https://www.ncbi.nlm.nih.gov/pubmed/26690143
http://dx.doi.org/10.3390/ijms161226170

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