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Calycosin Suppresses RANKL-Mediated Osteoclastogenesis through Inhibition of MAPKs and NF-κB

Calycosin, an isoflavonoid phytoestrogen, isolated from Radix Astragali, was reported to possess anti-tumor, anti-inflammation, and osteogenic properties, but its impact on osteoclast differentiation remains unclear. In this study, we examined the effects of calycosin on osteoclastogenesis induced b...

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Detalles Bibliográficos
Autores principales: Quan, Gui-Hua, Wang, Hongbing, Cao, Jinjin, Zhang, Yuxin, Wu, Donglin, Peng, Qisheng, Liu, Ning, Sun, Wan-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691122/
https://www.ncbi.nlm.nih.gov/pubmed/26690415
http://dx.doi.org/10.3390/ijms161226179