Association of the rs1346044 Polymorphism of the Werner Syndrome Gene RECQL2 with Increased Risk and Premature Onset of Breast Cancer

Like other RECQ helicases, WRN/RECQL2 plays a crucial role in DNA replication and the maintenance of genome stability. Inactivating mutations in RECQL2 lead to Werner syndrome, a rare autosomal disease associated with premature aging and an increased susceptibility to multiple cancer types. We analy...

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Detalles Bibliográficos
Autores principales: Zins, Karin, Frech, Barbara, Taubenschuss, Eva, Schneeberger, Christian, Abraham, Dietmar, Schreiber, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691135/
https://www.ncbi.nlm.nih.gov/pubmed/26690424
http://dx.doi.org/10.3390/ijms161226192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691135/
https://www.ncbi.nlm.nih.gov/pubmed/26690424
http://dx.doi.org/10.3390/ijms161226192

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