Histone H2AX Is Involved in FoxO3a-Mediated Transcriptional Responses to Ionizing Radiation to Maintain Genome Stability

Histone H2AX plays a crucial role in molecular and cellular responses to DNA damage and in the maintenance of genome stability. It is downstream of ataxia telangiectasia mutated (ATM) damage signaling pathway and there is an emerging role of the transcription factor FoxO3a, a regulator of a variety...

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Detalles Bibliográficos
Autores principales: Tarrade, Stephane, Bhardwaj, Tanya, Flegal, Matthew, Bertrand, Lindsey, Velegzhaninov, Ilya, Moskalev, Alexey, Klokov, Dmitry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691159/
https://www.ncbi.nlm.nih.gov/pubmed/26694365
http://dx.doi.org/10.3390/ijms161226216

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691159/
https://www.ncbi.nlm.nih.gov/pubmed/26694365
http://dx.doi.org/10.3390/ijms161226216

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