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Histone H2AX Is Involved in FoxO3a-Mediated Transcriptional Responses to Ionizing Radiation to Maintain Genome Stability
Histone H2AX plays a crucial role in molecular and cellular responses to DNA damage and in the maintenance of genome stability. It is downstream of ataxia telangiectasia mutated (ATM) damage signaling pathway and there is an emerging role of the transcription factor FoxO3a, a regulator of a variety...
Autores principales: | Tarrade, Stephane, Bhardwaj, Tanya, Flegal, Matthew, Bertrand, Lindsey, Velegzhaninov, Ilya, Moskalev, Alexey, Klokov, Dmitry |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691159/ https://www.ncbi.nlm.nih.gov/pubmed/26694365 http://dx.doi.org/10.3390/ijms161226216 |
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