FLIP the Switch: Regulation of Apoptosis and Necroptosis by cFLIP

cFLIP (cellular FLICE-like inhibitory protein) is structurally related to caspase-8 but lacks proteolytic activity due to multiple amino acid substitutions of catalytically important residues. cFLIP protein is evolutionarily conserved and expressed as three functionally different isoforms in humans...

Descripción completa

Detalles Bibliográficos
Autores principales: Tsuchiya, Yuichi, Nakabayashi, Osamu, Nakano, Hiroyasu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691174/
https://www.ncbi.nlm.nih.gov/pubmed/26694384
http://dx.doi.org/10.3390/ijms161226232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691174/
https://www.ncbi.nlm.nih.gov/pubmed/26694384
http://dx.doi.org/10.3390/ijms161226232

Ejemplares similares