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FLIP the Switch: Regulation of Apoptosis and Necroptosis by cFLIP

cFLIP (cellular FLICE-like inhibitory protein) is structurally related to caspase-8 but lacks proteolytic activity due to multiple amino acid substitutions of catalytically important residues. cFLIP protein is evolutionarily conserved and expressed as three functionally different isoforms in humans...

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Detalles Bibliográficos
Autores principales:	Tsuchiya, Yuichi, Nakabayashi, Osamu, Nakano, Hiroyasu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691174/ https://www.ncbi.nlm.nih.gov/pubmed/26694384 http://dx.doi.org/10.3390/ijms161226232

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