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Interaction of βA3-Crystallin with Deamidated Mutants of αA- and αB-Crystallins

Interaction among crystallins is required for the maintenance of lens transparency. Deamidation is one of the most common post-translational modifications in crystallins, which results in incorrect interaction and leads to aggregate formation. Various studies have established interaction among the α...

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Detalles Bibliográficos
Autores principales: Tiwary, Ekta, Hegde, Shylaja, Purushotham, Sangeetha, Deivanayagam, Champion, Srivastava, Om
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691197/
https://www.ncbi.nlm.nih.gov/pubmed/26657544
http://dx.doi.org/10.1371/journal.pone.0144621