Mother Centriole Distal Appendages Mediate Centrosome Docking at the Immunological Synapse and Reveal Mechanistic Parallels with Ciliogenesis

Cytotoxic T lymphocytes (CTLs) are highly effective serial killers capable of destroying virally infected and cancerous targets by polarized release from secretory lysosomes. Upon target contact, the CTL centrosome rapidly moves to the immunological synapse, focusing microtubule-directed release at...

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Detalles Bibliográficos
Autores principales: Stinchcombe, Jane C., Randzavola, Lyra O., Angus, Karen L., Mantell, Judith M., Verkade, Paul, Griffiths, Gillian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691242/
https://www.ncbi.nlm.nih.gov/pubmed/26670998
http://dx.doi.org/10.1016/j.cub.2015.10.028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691242/
https://www.ncbi.nlm.nih.gov/pubmed/26670998
http://dx.doi.org/10.1016/j.cub.2015.10.028

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