DGCR8 Acts as an Adaptor for the Exosome Complex to Degrade Double-Stranded Structured RNAs

The Microprocessor complex (DGCR8/Drosha) is required for microRNA (miRNA) biogenesis but also binds and regulates the stability of several types of cellular RNAs. Of particular interest, DGCR8 controls the stability of mature small nucleolar RNA (snoRNA) transcripts independently of Drosha, suggest...

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Detalles Bibliográficos
Autores principales: Macias, Sara, Cordiner, Ross A., Gautier, Philippe, Plass, Mireya, Cáceres, Javier F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691244/
https://www.ncbi.nlm.nih.gov/pubmed/26687677
http://dx.doi.org/10.1016/j.molcel.2015.11.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691244/
https://www.ncbi.nlm.nih.gov/pubmed/26687677
http://dx.doi.org/10.1016/j.molcel.2015.11.011

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