The MMP-1/PAR-1 Axis Enhances Proliferation and Neuronal Differentiation of Adult Hippocampal Neural Progenitor Cells

Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases that play a role in varied forms of developmental and postnatal neuroplasticity. MMP substrates include protease-activated receptor-1 (PAR-1), a G-protein coupled receptor expressed in hippocampus. We examined proliferation and diffe...

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Detalles Bibliográficos
Autores principales: Valente, Maria Maddalena, Allen, Megan, Bortolotto, Valeria, Lim, Seung T., Conant, Katherine, Grilli, Mariagrazia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691474/
https://www.ncbi.nlm.nih.gov/pubmed/26783471
http://dx.doi.org/10.1155/2015/646595

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691474/
https://www.ncbi.nlm.nih.gov/pubmed/26783471
http://dx.doi.org/10.1155/2015/646595

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