Exogenous Heparan Sulfate Enhances the TGF-β3-Induced Chondrogenesis in Human Mesenchymal Stem Cells by Activating TGF-β/Smad Signaling

Heparan sulfate (HS) interacts with growth factors and has been implicated in regulating chondrogenesis. However, the effect of HS on TGF-β-mediated mesenchymal stem cell (MSC) chondrogenesis and molecular mechanisms remains unknown. In this study, we explored the effects of exogenous HS alone and i...

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Detalles Bibliográficos
Autores principales: Chen, Juan, Wang, Yongqian, Chen, Chong, Lian, Chengjie, Zhou, Taifeng, Gao, Bo, Wu, Zizhao, Xu, Caixia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691498/
https://www.ncbi.nlm.nih.gov/pubmed/26783399
http://dx.doi.org/10.1155/2016/1520136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691498/
https://www.ncbi.nlm.nih.gov/pubmed/26783399
http://dx.doi.org/10.1155/2016/1520136

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