Apocynin and Diphenyleneiodonium Induce Oxidative Stress and Modulate PI3K/Akt and MAPK/Erk Activity in Mouse Embryonic Stem Cells

Reactive oxygen species (ROS) are important regulators of cellular functions. In embryonic stem cells, ROS are suggested to influence differentiation status. Regulated ROS formation is catalyzed primarily by NADPH-dependent oxidases (NOXs). Apocynin and diphenyleneiodonium are frequently used inhibi...

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Detalles Bibliográficos
Autores principales: Kučera, Jan, Binó, Lucia, Štefková, Kateřina, Jaroš, Josef, Vašíček, Ondřej, Večeřa, Josef, Kubala, Lukáš, Pacherník, Jiří
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691611/
https://www.ncbi.nlm.nih.gov/pubmed/26788250
http://dx.doi.org/10.1155/2016/7409196

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691611/
https://www.ncbi.nlm.nih.gov/pubmed/26788250
http://dx.doi.org/10.1155/2016/7409196

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