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Apocynin and Diphenyleneiodonium Induce Oxidative Stress and Modulate PI3K/Akt and MAPK/Erk Activity in Mouse Embryonic Stem Cells
Reactive oxygen species (ROS) are important regulators of cellular functions. In embryonic stem cells, ROS are suggested to influence differentiation status. Regulated ROS formation is catalyzed primarily by NADPH-dependent oxidases (NOXs). Apocynin and diphenyleneiodonium are frequently used inhibi...
Autores principales: | Kučera, Jan, Binó, Lucia, Štefková, Kateřina, Jaroš, Josef, Vašíček, Ondřej, Večeřa, Josef, Kubala, Lukáš, Pacherník, Jiří |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691611/ https://www.ncbi.nlm.nih.gov/pubmed/26788250 http://dx.doi.org/10.1155/2016/7409196 |
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