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Connexin-Based Therapeutics and Tissue Engineering Approaches to the Amelioration of Chronic Pancreatitis and Type I Diabetes: Construction and Characterization of a Novel Prevascularized Bioartificial Pancreas

Total pancreatectomy and islet autotransplantation is a cutting-edge technique to treat chronic pancreatitis and postoperative diabetes. A major obstacle has been low islet cell survival due largely to the innate inflammatory response. Connexin43 (Cx43) channels play a key role in early inflammation...

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Detalles Bibliográficos
Autores principales: Rhett, J. Matthew, Wang, Hongjun, Bainbridge, Heather, Song, Lili, Yost, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691620/
https://www.ncbi.nlm.nih.gov/pubmed/26788521
http://dx.doi.org/10.1155/2016/7262680