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Cdk5r1 Overexpression Induces Primary β-Cell Proliferation

Decreased β-cell mass is a hallmark of type 1 and type 2 diabetes. Islet transplantation as a method of diabetes therapy is hampered by the paucity of transplant ready islets. Understanding the pathways controlling islet proliferation may be used to increase functional β-cell mass through transplant...

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Detalles Bibliográficos
Autores principales: Draney, Carrie, Hobson, Amanda E., Grover, Samuel G., Jack, Benjamin O., Tessem, Jeffery S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691621/
https://www.ncbi.nlm.nih.gov/pubmed/26788519
http://dx.doi.org/10.1155/2016/6375804